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Radical prostatectomy
Radical prostatectomy (surgical removal of the prostate) offers the possibility of a cure only if the cancer has not spread to the lymph nodes in the pelvis or to other parts of the body. Therefore, when the risk of spread is judged to be high, some surgeons perform a laparoscopic biopsy to obtain samples of the lymph nodes before the planned prostatectomy; others sample the lymph nodes at the time of the scheduled prostatectomy and discontinue the operation if the cancer has spread. However, it is uncommon today (because of PSA testing) to find disease that has spread to the lymph nodes at the time of surgery. If enlarged lymph nodes are discovered on a CT scan or MRI, a fine needle biopsy to remove some cells from the lymph nodes may be performed to determine whether the cancer has spread.
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Radical prostatectomy is the only treatment for localized prostate cancer (cancer confined to the prostate) that has been proven to reduce deaths from the disease. A study published in 2002 found that Swedish men randomized to radical prostatectomy had a 50 percent reduction in their risk of dying of prostate cancer eight years after diagnosis, compared with men randomized to watchful waiting.
Rare complications of radical prostatectomy include narrowing of the urethra (urethral stricture), damage to the rectum, and the surgical and anesthetic risks (including death) that accompany any operation.
Some surgeons are using laparoscopy to perform radical prostatectomy. The laparoscopic procedure is less invasive than traditional prostatectomy; it requires five tiny incisions on the abdomen rather than one long one. It is still considered an evolving procedure, however.
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