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Saturday, July 26, 2008
Brain & Behavior Center
Anxiety
AboutSymptomsTreatmentManaging

Treating generalized anxiety disorder

Despite its more chronic course, GAD responds better to treatment than panic disorder. Psychotherapy benefits many people, either by itself or in combination with medication. In addition, relaxation techniques, such as deep breathing exercises or meditation, may relieve symptoms of GAD.

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Venlafaxine (Effexor) and paroxetine have both received FDA approval for the treatment of GAD, but other serotonin and norepinephrine reuptake inhibitors, SSRIs, tricyclics, buspirone, and benzodiazepines, such as alprazolam and diazepam (Valium), are also used. A 2003 study from the American Journal of Psychiatry found that significantly more patients with GAD who took 40 mg of paroxetine for eight weeks experienced a significant reduction in symptoms than those who took a placebo (68 percent vs. 46 percent).

Persistent GAD symptoms can lead to depression and abuse of alcohol and drugs--especially of benzodiazepines. Treatment with benzodiazepines should be limited to short (five to seven days) courses to avoid dependence. Buspirone may be a better option because it does not cause dependence or withdrawal symptoms. Cutting back on caffeine may also help ease the symptoms of GAD.

Content last updated: 3/28/06Previous PagePrevious page Next PageNext Page



Content excerpted from the Johns Hopkins White Paper on Depression and Anxiety.




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