H2 Receptor Antagonists

Does heartburn keep you up at night? There are several over-the-counter treatment options to explore. H2 receptor antagonists help to reduce the production of stomach acid and are intended to relieve and prevent heartburn. Antacids, on the other hand, neutralize stomach acid after it's splashed into the esophagus. Also see acid reducers and proton pump inhibitors.

Product Name Percent of Pharmacists' Votes
Zantac 150 37.0%
Pepcid AC 30.0%
Pepcid Complete 20.0%
Zantac 75 8.0%
Tums Dual Action 4.0%
Tagamet HB 200 1.0%

See Other H2 Receptor Antagonists Products

Acid Reducers

Heartburn is the result of stomach acid splashing back into the esophagus, which creates a burning feeling. Many of the products below help to reduce the production of stomach acid. Also check out antacids, which neutralize stomach acid.

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Does that spicy burrito you just ate make it feel like your chest is on fire? Certain foods, including chocolate and coffee, as well as alcohol and cigarettes can trigger heartburn—the painful feeling that occurs when acidic stomach juices wash back into the esophagus. The products below may help to neutralize that acid. Also see acid reducers and upset stomach remedies.

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Please consult your doctor or pharmacist for specific guidance on health products that may be appropriate for you. While U.S. News lists the results of the pharmacist survey, U.S. News does not recommend or endorse any health products listed here. Please see Disclaimer and a Note About Your Health. Read about the pharmacist survey here.


These pharmacist-recommended over-the-counter products will make your next trip to the drugstore easier. See more>>

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