"I think this issue needs to be looked at a bit more, and the method of delivery and other factors need to be looked at in more detail," he said.
This study didn't compare metered dose inhalers to nebulizers, but both Appleyard and Horovitz said it's likely that the entire dose of medication from an inhaler doesn't make it to the lungs either. Both said, however, that drug companies have to take these factors into account before getting approval from the U.S. Food and Drug Administration.
For his part, Kantar said, "Our study confirms the need for prescribers, researchers and regulators to have information on both the prescribed dose and the dose patients are likely to inhale from their nebulizer to allow informed interpretation of clinical effect and side effects."
Learn more about asthma medications from the American Lung Association.
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