The study noted that the U.S. Food and Drug Administration plans to launch a similar anti-tobacco campaign in 2014 targeting teenagers and young adults.
Nonprofit anti-tobacco groups like the American Cancer Society also might take the lessons from the CDC campaign and use them in their own ad efforts, Glynn said. It is likely, however, that only a coalition of several or many groups would be able to have the same impact as the CDC campaign.
"It is expensive. It cost about $54 million, which for most organizations would be a very big spend," Glynn said. "The CDC is in the best position to do this."
Group efforts will be needed to combat the tobacco industry, which spent $8.6 billion on advertising in 2011, he said.
McAfee said the CDC estimates as many as 330,000 years of life were saved as a result of people quitting smoking due to the campaign.
"That adds up to less than $200 we spent per year of life saved," he said. "It's like the bargain of the century for public health."
To find out more about how to quit smoking, visit Smokefree.gov.
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