While the vaccine was given to patients in other countries and yielded good results, it was never approved for use in the United States. But by demonstrating that a live-virus polio vaccine could be safe and effective, Koprowski opened the door to the live-virus oral vaccine that was developed by Albert Sabin and introduced in the 1960s.
Koprowski, who died April 11, was considered one of the leading biomedical researchers in the world. Along with the first live-virus polio vaccine, his notable accomplishments included developing a safer, less painful and more effective rabies vaccine that is still widely used, the Times reported.
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