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dsinlaof CA11:54AM August 10, 2009
`The HIV RNA genome is huge, composed of two strands of almost 10,000 nucleotides each`
.. and it needed O-n-l-y 20 years to decode it ?!
Human DNA ~ 3 Billion !
it's verrry confusing!
Vladimir Orlovskyof CA8:42PM August 06, 2009
Sorry, this article and others covering this story are very misleading. Scientists have sequenced the complete genome of hundreds of strains of HIV over the past 20 years. So in terms of genomic sequence there is nothing new here at all. From what I can gather it looks like Kevin Weeks et al. have mapped the secondary or tertiary structure of the viral RNA genome. Thus they are describing what the viral RNA genome looks like in 2D or 3D space. This is important since it can show which regions of the viral RNA are open and perhaps accessible to novel drug treatments like small interfering (si) RNAs. There is a big difference between primary sequence, secondary (2 dimensional), and tertiary (3 dimensional) structure. Simply reporting that scientist have "decoded" the HIV genome for the first time is not accurate. [Rant mode off]
WCSdncrof AZ3:54PM August 06, 2009
Let's randomly mutate it and see how it responds. Mutate it. Seriously? This is the great idea that they came up with? This is the type of stuff you get on SyFy where a genius mutates the bug and now instead of it requiring sharing bodily fluids, it becomes airborne.
Thanks. This is great news.
Pat A.of 2:08PM August 06, 2009
I've experienced first hand what is like to see a loved one ill from this devastating disease. It's been so heartbreaking for me but I'm hopeful that there will be a cure. Nobody should continue to die from this terrible disease and we all as a human race should "step up" when people like the Governor of California starts to cut on programs that help HIV Positive and AIDS patients. WE SHOULD BE STEPPING FORWARD NOT TAKING STEPS BACKWARDS TO FIND A CURE. IT AFFECTS ALL OF US!
Wendy Mof CA5:40AM August 06, 2009
Great work! I hope this is a milestone step in the journey for a cure. This disease has been so cruel and devastating. I also hope this gives hope to those struggling with the disease. Stay strong!
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Eddie of MO 5:41PM October 20, 2009
dsinla of CA 11:54AM August 10, 2009
Vladimir Orlovsky of CA 8:42PM August 06, 2009
WCSdncr of AZ 3:54PM August 06, 2009
Pat A. of 2:08PM August 06, 2009
Wendy M of CA 5:40AM August 06, 2009
Gordon Stone of AZ 1:54AM August 06, 2009