Resveratrol and CoQ10 Supplements Are Popular—But Unproven

'Just wondering why there aren't reliable scientific studies on such popular supplements. Maybe big pharma doesn't want us to know something?

Jorge of OR 12:14PM September 27, 2011

I must say that for the last 3 months I have taken the 250 mg version of Resveratrol with active ubiquinol so tHe Converstion is enhanced.( I am over 40) th.e brand I use is named Resvereage and is organic. So far great results.

Paul c. of NC 12:20AM August 04, 2010

Decades of research have been done with an ordinary, oxidized form of CoQ10 called ubiquinone. However, recently Japanese scientists made a breakthrough that allowed for commercial forms of ubiquinol (called Kaneka QH) to be produced. Ubiquinol has been studied in athletes, and it has been shown to reduce biomarkers known to correlate with muscle damage. Additionally, QH has been shown to improve edothelial function, thus improving circulation. Those under oxidative stress, i.e. diabetics, have particularly low levels of QH in the body, indicative of loss of correct redox balance.

Bottom Line

I think that Ubiquinol is the way to go for sparking stimulant-free elevations in physical performance, and this is being validated as we speak at University institutions. Ubiquinol is a proven supplement and its benefits are enormous. Give it a try.

Sid Shastri of CA 11:49PM March 06, 2010

I became aware of Ubiquinol in July 2009 by reading the literature on CoQ10. I immediately changed from CoQ10 to Ubiquinol and noticed a pronounced improvement in my health and vigor. Most noticeable are improved periodontal health, regeneration of cuticles lost to eczema forty years ago, prevention of athletes foot, increased exercise capacity for intensity but not yet endurance, repair of tendon strain, thicker footpad and finger tip callous, increased production of cerumen. I did a saturation experiment on self. At saturation I get a tingling/numbness in fingertips and toes. I cannot say for certain whether the sensation is more or less sensitivity. My brother and uncle related by mitochondrial inheritance experienced the same. The sensation is reversible with reduced dose for all of us. My formula for dose is to assume production of 500 mg/day at age 26. Expect production to decline by half for every twenty years after age 26. In practice I tolerate 200 mg/day at age 62. I estimate the earliest a person would NOTICE benefit from CoQ10/ubiquinol supplements is age 40-50. Ubiquinol is a boon. However, geriatric patients need many other supplements, and vigorous exercise as well. As a young athlete I was in constant pain from exercise. I now understand that the normal pain from vigorous exercise is necessary to maintain the health of youth. Ubiquinol helps me retain the ability to exert effort and challenge my limits. Ubiquinol does not get me into the gym and out on the running field. CoQ10 studies on athletic performance show no improvement with CoQ10 supplements. The studies all involved trained athletes in the prime of life. Such studies should be repeated with ubiquinol and geriatric athletes if any performance improvement is to be shown. Unfortunately there are not enough geriatric athletes available for study. An acquaintance suffered stroke and paralysis while taking CoQ10. She recovered 100%. The literature documents similar recovery from stroke aided by CoQ10. I estimate her age at 40. She had high blood pressure. Although this is an isolated event my own experience with improved cell proliferation with ubiquinol supplements suggests that ubiquinol should be used to repair brain injury. CoQ10 is documented to improve repair of heart injuries. Repair of joint, tendon injuries, and emphysema are speculative, but I have the notion. Likewise speculative are periodontal bone repair, and immune response to terminal lung infection. For sure I see no improvement in my own presbyopia, a free radical cross link impairment. Ubiquinol improves energy production in old systems. I am reminded of a discussion of automobile improvements with a mechanic. He said everything runs better with more horsepower.

Keith Beatty of CA 5:07AM February 19, 2010