Study: New Drug For Hodgkin's Lymphoma
An experimental drug shows promise against Hodgkin's lymphoma in people who either relapsed or didn't respond to standard chemotherapy treatment. The drug, called SGN-35, wiped out tumors in one-third of patients, and reduced tumor size by half in another 40 percent, according to study results presented Sunday at an American Society of Hematology meeting in Orlando, Fla. Nearly 95 percent of the 102 participants saw their tumors shrink by at least 25 percent, which is considered a strong sign of recovery. SGN-35, manufactured by Seattle Genetics, uses an antibody that recognizes and connects to receptors on the surface of malignant cells, and releases a chemical that kills them by stopping their ability to divide. Because the drug only targets cancer cells—chemicals don't enter the bloodstream or affect healthy tissues—it can be given at high doses, without inflicting the side effects typical of chemotherapy. "This is unheard of for a single drug," study author Robert Chen told The Seattle Times. "Within a week, you could see some patients get better. You're going to see more cures, and you're going to buy a lot more time for patients who previously were destined for hospice." Seattle Genetics expects the drug will be approved by U.S. regulators by the end of 2011.
P90X Workout Program: Really the Best for Burning Fat, Building Muscles?
Have you heard of the latest fitness phenomenon that has folks working out like crazy six times a week? It's called P90X, and it's one of the top 5 fitness DVDs on Amazon.com. The program, which some users consider to be more like a newfound religion, employs lifting weights using a technique called muscle confusion. This involves switching-up resistance training exercises so your body doesn't become accustomed to the same repetitive movements every time you work out, fitness blogger Chelsea Bush writes for U.S. News. If your body adapts too well to your workouts, the theory goes, it won't build muscle as efficiently as when it's faced with unpredictable movements. Hence, the confusion.
Fitness trainers who teach muscle confusion techniques say that the ultimate goal is to avoid that muscle building plateau that most of us face when we've been lifting weights for a while. "The goal is to keep the body guessing," says John Romaniello, a New York-based trainer and creator of the Final Phase Fat Loss training system, a muscle confusion program that can be downloaded for purchase. "Once your muscles adapt, your body will become more proficient at a certain movement or type of exercise. You'll use less energy and thus see diminishing returns," he explains. [Read more: P90X Workout Program: Really the Best for Burning Fat, Building Muscles?]
10 HIV/AIDS Beliefs—Which Ones Are True?
As if waging war against an incurable virus that plagues 33 million people globally weren't enough, researchers, doctors, and public health officials on last week's World AIDS Day continue to battle yet another elusive problem: misinformation, U.S. News's Kurtis Hiatt reports.
"It really does obstruct the fight," says Rowena Johnston, vice president and director of research at amfAR, a nonprofit that funds HIV/AIDS research. Broaching topics like sex and drug use—the major vehicles for transmission—is "taboo" for many, she says, "so a challenge certainly is getting people to talk openly and honestly about what HIV is and isn't." And part of a candid conversation, she says, should be devoted to debunking the myths many have come to believe, including the following:
1. If I had HIV, I would know. Not the case, says Kimberly Hagen, assistant director for the Center for AIDS Research at Emory University in Atlanta. About 1.1 million people in the United States are HIV-positive, and as many as 1 in 5 don't know it, estimates the Centers for Disease Control and Prevention. Many of them feel perfectly healthy. And those who have symptoms may confuse them with run-of-the-mill flu. Denial also plays a role, say experts. "There is a universal tendency with HIV," says Hagen, to try to say, " 'This is something that will affect someone else and not me.' And so you say that you can't get it doing the things that you do—you can only get it doing the things that other people do. That may be the biggest myth." [Read more: 10 HIV/AIDS Beliefs—Which Ones Are True?]
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