- Blood Clot Drug Causes Higher Death Rate in Elderly Patients, Maker Says
- Family History Doesn't Impact Prostate Cancer Treatment
- One Way to Thwart Disease: Make Mosquitoes Die Earlier
- New Immunization Recommendations for Children Unveiled
- New Year's Resolution: Restock That Medicine Cabinet
- Drug Makers Agree to Voluntary Ban on Doctor 'Freebies'
Here are some of the latest health and medical news developments, compiled by editors of HealthDay:
Blood Clot Drug Causes Higher Death Rate in Elderly Patients, Maker Says
A drug used to treat blood clots formed primarily from deep vein thrombosis or in kidney failure increases the death rate among elderly patients, its maker has warned physicians.
According to the Associated Press, the biotech company Celgene Corp. has alerted doctors in a letter also posted on the U.S. Food and Drug Administration Web site, stating that clinical trials using the drug Innohep showed a death increase incidence in patients over age 70 of 13 percent, compared to a death rate of 5 percent when another anti-clotting drug, Heparin, was used.
Celgene had warned doctors in a July 2008 letter that the incidence of death among patients over age 90 was higher when Innohep was used, but the latest letter expanded the warning to "all elderly patients," the A.P. reported.
The study involved 350 patients with deep vein thrombosis who were getting Innohep, and it was stopped in February, 2008, after the mortality results were analyzed. The Innohep group died of various causes, the wire service reported, so no single cause of death stood out.
The FDA stated that it had asked Celgen to revise the information on the Innophep package "to better describe the overall study results which suggest that, when compared to (heparin), Innohep increases the risk of death for elderly patients" with failing kidneys, the A.P. said.
Family History Doesn't Impact Prostate Cancer Treatment
The outcomes of prostate cancer patients treated with brachytherapy (seed implants) were not affected by patients' family history, a new study finds.
Researchers from the Departments of Radiation Oncology and Urology at New York City's Mount Sinai School of Medicine tracked 1,738 prostate cancer patients, of which 187 had a family history of the disease. The scientists found that among all risk groups, family history had no significance on outcome among prostate cancer patients treated with brachytherapy.
Study results were reported in the Jan. 1 issue of the International Journal of Radiation Oncology *Biology* Physics.
Prostate cancer is the second-most common cancer in men, next to skin cancer. The American Cancer Society estimates that 186,320 new cases of prostate cancer were diagnosed in the United States in 2008, and some 28,660 men died of the disease.
While family history does increase a man's risk of developing prostate cancer, "there is conflicting data on how family history impacts treatment outcomes," the researchers wrote in a news release.
One Way to Thwart Disease: Make Mosquitoes Die Earlier
Since older mosquitoes are more likely to harbor diseases that can be passed to people, Australian researchers say they may have found a way to stem the process: make the mosquitoes die younger.
Dengue fever and malaria are examples of mosquito-borne diseases that have stricken millions of people worldwide. It takes about two weeks for mosquitoes to acquire and incubate the pathogens that cause these diseases and then spread them to people, the Associated Press reported.
So scientists at the University of Queensland tried introducing mosquitoes to a bacterial parasite that wound up cutting the insects' lifespan by about half, to an average of 21 days from 50 days, the wire service reported.
Writing in the journal Science, lead researcher Scott O'Neill said the discovery could prove to be a safer alternative to the widespread use of insecticides.
If the parasite could spread among enough disease-carrying mosquitoes, the method "may provide an inexpensive approach in dengue control," he wrote.
New Immunization Recommendations for Children Unveiled