Why Is Lung Cancer Rising Among Nonsmoking Women?

One in five women with lung cancer has never smoked, and the diagnosis rate among women is only increasing.

Rebecca Falzano, 32, with her husband and daughter. She has not had traces of lung cancer since her surgery three years ago.

For years when Rebecca Falzano was living in New York City, she woke up every morning wheezing and catching her breath. Her doctor told her she had asthma, but no inhaler fixed her difficult breathing.

She thought she would get better when she moved to Maine – what she knew as home of the Breathe Easy Coalition – but her symptoms got worse. Finally, her doctor recommended a CT scan. She was floored by the result: There was a tumor on her lung.

"This blindsided me as a 28-year-old, active, nonsmoking woman," she says. "I had a lot of the stereotypical thoughts about lung cancer. I thought it was a smoker's disease. I thought, 'How could I possibly have this?'"

Falzano is among one in five women who has lung cancer but has never smoked. She and others with the disease struggle with the stigma tied to lung cancer – when Falzano tells people about her disease, their first question is whether she smoked. She often responds, "Why does that matter?" Lung cancer advocates like Lecia Sequist, a medical oncologist at Massachusetts General Hospital Cancer Center and associate professor of medicine at Harvard Medical School, say too much shame and guilt is imparted on those with the disease, and it prevents people from talking about lung cancer, which leads to little awareness and advocacy.

Falzano had surgery a month after she was diagnosed in 2010 and then married her husband four months later – balancing wedding planning and an excruciating recovery. Now 32, she works as an editor of a home design magazine in Portland, Maine, and is focusing on being a new parent to a healthy baby girl. "Cancer is never a gift," she says, "but it is certainly an opportunity to evaluate what's important in life."

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Lung Cancer: The Deadliest Cancer

Lung cancer takes more lives than breast, prostate, colon and pancreatic cancer combined, according to the American Lung Association. The five-year survival rate for those diagnosed with lung cancer is 16 percent. Sequist says there have been some breakthroughs in treatments. The lung cancer rate has fallen 21 percent among men, but for reasons that remain unclear, the rates have risen 116 percent among women. About 160,000 people die from lung cancer every year, according to the National Cancer Institute, and more than half die within one year of being diagnosed.


Diane Legg has lived with late-stage lung cancer for seven years. She is pictured here with her husband and three boys.

Diane Legg, 51, has lived with late-stage lung cancer for seven years. Doctors discovered the growth by accident in 2004, through a CT scan that was meant to check on a pulled back muscle. When she went to see a pulmonologist, he told her it was highly unlikely she had lung cancer given her health history. Still, she knew anyone could be affected. A friend, who was also a nonsmoker and had a healthy lifestyle, was diagnosed with lung cancer four months earlier. During Legg's biopsy, her friend was at the back of her mind. She thought, "Could this happen to me, too?"

The doctor called her and confirmed she had lung cancer. "It was absolutely shocking and appalling," she says.

Legg underwent surgery and chemotherapy. Throughout the treatment, she continued to work in industrial sales for General Electric. Her friend had undergone the same treatment, but died only nine months after she was diagnosed. As a result, Legg became heavily involved in advocacy and awareness efforts.

Her lung cancer returned in 2006. The tumors are growing slowly, so she isn't undergoing treatment, but will do so in a few months. She suffers shortness of breath, fatigue and coughing. She resigned from her job to focus on her health and has become heavily involved in LUNGstrong, a nonprofit she founded that raises money for lung cancer research. She's also focusing on her husband and three boys. "The most important thing for me during my entire life was to be a mom," she says. She also does endurance sports and says lung cancer hasn't stopped her from living an active life. "Having a respiratory disease, but being able to do such physical activities has been freeing for me," she says.