2. Over-the-counter peptide creams
Creams containing peptides—short snippets of linked amino acids—can be useful for reducing the appearance of wrinkles and fine lines, but they haven't been shown to work as well as retinoids. As skin ages, it loses collagen and becomes wrinkled and thin; creams containing peptides are supposed to encourage the skin to make new collagen. Peptides are found in a variety of products, from the inexpensive to the very expensive, but you don't have to ante up to get their benefit, advises Jeffrey Benabio, a dermatologist who writes The Dermatology Blog; he says Oil of Olay Regenerist (which costs less than $20) is as good as the pricey stuff.