Wednesday, November 25, 2009

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Heart to Heart Blog - U.S. News & World Report

CRP Heart Test May Lead to Overuse of Statins Like Crestor

November 11, 2008 03:01 PM ET | Bernadine Healy, M.D. | Permanent Link | Print

Reader Comments

statins

my Dr. and my rheumatologist want me to start statins to reduce my 4.7 CRP.But I have a 95 HDL. What do you think? barrera

statins

my Dr. and my rheumatologist want me to start statins to reduce my 4.7 CRP.But I have a 95 HDL. What do you think? barrera

long term side effects of Statins

Physicians are already passing out statin prescriptions like they are candy, with scant regard for cost and long term problems. ALL statins work by blocking an enzyme (HMG Co A reductase) that also lets our bodies produce CoQ 10, a substance that is necessary for proper heart function.

Here is my prediction- in the next five years, we will see an explosion of physician-induced congestive heart failure, from undiagnosed CoQ 10 deficiency brought on by our wanton oveprescribing of statin meds.

Many natural supplements can cut CRP in half. I have found that everything statins do, magnesium (800 mg a day) does better. Fish oils also have natural anti-inflammatory action. These are very safe, effective and inexpensive products.

A less known side effect of statins is global amnesia. I believe that pilots are restricted from flying if they are taking statin drugs.

I hate to see my colleagues use the "Symptom? Drug!! Next patient, please," mindless approach to medicine. With a little thought, and better knowledge of the medicinal use of natural substances, physicians can help patients achieve much better quality of health, at a fraction of the present costs.

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gingivitis and c-reactive protein.

The cure for gingivitis, which will lower c-reactive protein in the blood is the amino acid lysine and vitamin c, which, incidentally, was prescribed by Dr. Linus Pauling, Nobel Laureate (twice) who lived into his 90's (93 or 94). Statins are sold by big pharma to unsuspecting consumers via the medical profession, which wouldn't exist in its present form without big pharma (res ipsa loquitor -- "the thing speaks for itself").

Generic statins save money

I looked up the price for Crestor 10 mg on drugstore.com. It was $111 for 30 tablets. With my RxDrugCard I can get 30 Simvastatin 10 mg for $8. If it turns out that one statin is as good as another, I'm going for the generic!!

Caution

With statins as a class of medications:

A.E.s are often under-reported with high doses of potent statins in particular. Additionally, there is no reduction in mortality or increase in the lifespan of one on statin therapy.

Several risk factors should determine if one is placed on statin therapy, and not just one, for reasons such as these.

Statins do decrease CV events and risks significantly. The meds. increase endothelial function, stabilize coronary plaque build up, and decrease thrombus formation. Maximum reduction in LDL is evaluated after about a month of therapy.

There is evidence to suggest that statins have other benefits besides lowering LDL, such as reducing inflammation (CRP), those with dementia or Parkinson's disease, and some forms of Cancer and cataracts.

It appears those statins produced by fermentation, such as Zocor and Pravachol, have less myopathy than the other synthetic statins, possibly due to being more hydrophyllic.

Yet overall, the existing cholesterol lowering recommendation should be re-evaluated, as they may be over-exaggerated.

Children should have their activity and weight checked and controlled more than now so they do not have the arteries of one that is middle-aged, and a candidate for a statin drug, possibly, not to mention early onset diabetes

The way that I see it, something was going on with these patients that made them at increased risk of a CV event. Whether it was hsCRP or CRP or dental disease, the use of Crestor dramitically reduced events with minimal side effects. Sure, some people are going to have side effects and not be able to tolerate the medicine, however this also happens to patients taking placebol.

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About Heart to Heart

Bernadine Healy, M.D., U.S.News & World Report's health editor and author of the magazine’s On Health column, is the former head of the National Institutes of Health, the American Red Cross, and the College of Medicine and Public Health at Ohio State University. A cardiologist and author of two books, she spent more than 25 years practicing medicine. In this blog, she covers matters close to her heart, including cardiovascular disease and other important aspects of personal health and health policy.

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