Friday, November 27, 2009

Respiratory Disorders

Michael Jackson, Health Rumors, and Alpha-1 Antitrypsin Deficiency

News reports, perhaps misinformed, suggested that the King of Pop needs a lung transplant

Posted December 23, 2008

If Michael Jackson, or anyone else, is diagnosed, what do you recommend?
If Michael Jackson truly does have the disorder, I would recommend that immediate family members be tested, particularly siblings—[siblings] are at the most risk for having a similar deficiency state. In a family in which the parents are both carriers who don't have the full-blown disease, about every child has a 1 in 4 chance of having the full-blown deficiency. That's why we usually recommend that the siblings be tested. That way we can at least—if nothing else—encourage them to quit smoking because smoking is the most common precipitating cause of emphysema [or lung destruction] in alpha-1's.

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