'Phase 0' Trials Aim to Speed Cancer Drug Development

Study participants also need to be aware that phase 0 trials, like any trial, might involve invasive procedures, such as blood work and biopsies. Before enrolling in a study, people should ask how it might negatively impact them and how it would positively impact others, LoRusso said.

"Some people would say 'no' because they don't want to be a guinea pig, but there are people out there who want to advance the science for future patients if they can," she said.

More information

The U.S. National Cancer Institute has more on phase 0 trials.