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HealthDay

Health Highlights: Dec. 7, 2008

Posted December 7, 2008

  • Higher Intelligence Linked to Better Quality Sperm
  • FDA Officials Differ Over Asthma Drugs' Risks
  • WHO Sets Standards for Melamine Contamination in Foods
  • Alzheimer's Drug May Help Brain Cancer Patients

Here are some of the latest health and medical news developments, compiled by editors of HealthDay:

Higher Intelligence Linked to Better Quality Sperm

Data from U.S. veterans suggests that smarter men produce more, and more agile, sperm.

According to the BBC, researchers at the Institute of Medicine examined sperm samples from 425 Vietnam War-era U.S. veterans, collected in 1985 by the U.S. Centers for Disease Control and Prevention. The scientists looked at the volume and mobility of sperm, as well as scores from a variety of intelligence tests taken by the veterans.

The team found that, after ruling out factors such as age and lifestyle, higher intelligence was correlated with all three measures of sperm health -- numbers, density, and mobility.

The relationship was not strong, lead researcher Dr. Rosalind Arden told the BBC, "but our results do support the theoretically important 'fitness factor' idea." That theory suggests that certain genes work together to make certain individuals fitter, healthier and smarter.

This connection probably starts in the womb, one expert said.

"The fact that it's possible to detect a statistical relationship between intelligence and semen quality in adult men probably says more about the co-development of brain and testicles when the man was in his mother's womb, and therefore how well they function in adult life, rather than suggesting that playing Sudoku can somehow stimulate more sperm to be produced," Dr. Allan Pacey, a fertility expert at the University of Sheffield, U.K., told the BBC.

The findings were published in the journal Intelligence.

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FDA Officials Differ Over Asthma Drugs' Risks

Two members of the U.S. Food and Drug Administration said Friday that people with asthma risk serious respiratory problems -- and even death -- if they continue to use four popular asthma drugs -- Advair, Symbicort, Serevent and Foradil, The New York Times reported.

But not all members of the FDA share that view. The agency has called a special two-day meeting of outside advisers for next Wednesday and Thursday to discuss data on the drugs and make recommendations on their use.

The two officials, who work in the FDA's safety division, posted an assessment on the agency Web site on Friday, saying asthma sufferers of all ages should not take the medicines. But a third FDA official concluded that Advair and Symbicort are safe for adults, but that all four drugs should no longer be used by children 17 and younger, the Times said.

Dr. Badrul A. Chowdhury, head of the FDA's division of pulmonary and allergy products, said his assessment found that the risk of death connected with the drugs was small, and that banning their use "would be an extreme approach" that could lead asthmatics to rely on other risky medications, the newspaper said.

The Associated Press said the drugs, known as long-acting beta agonists (LABAs), already carry the FDA's strongest warnings on their labels. The medicines relax tight muscles around constricted airways, freeing asthma suffers from the need to take a puff from their inhaler every few hours. For many people with asthma, that means they can sleep through the night.

But for reasons still unclear, LABAs can increase the risk of death and respiratory complications in some patients. Those risks might be reduced if an LABA is used in tandem with a steroid to treat underlying inflammation in the airways. Current medical guidelines suggest using both kinds of drugs together for patients with chronic asthma who aren't responding well to other treatments, the AP said.

Dr. Katharine Knobil, global clinical vice president for GlaxoSmithKline, which markets both Advair and Serevent, told the Times that the FDA's drug-safety division findings weren't "supported by their own data." She said Advair was safe and Serevent was safe when used with a steroid.

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