Tuesday, November 24, 2009

Brain & Behavior

3 Lousy Reasons to Consider an Antidepressant Medication

As acceptance of psychiatric drugs rises, are people flocking to antidepressants for good reasons?

Posted August 6, 2009

New research shows Americans have become increasingly accepting of psychiatric medications such as antidepressants, the use of which is on the rise. For some people, the drugs are essential. But others appear willing to use antidepressants for reasons that experts say may be unwise.

Video: Learning About Depression
Video: Learning About Depression

Antidepressants are the most routinely prescribed class of drugs in the United States, according to a study out Monday in the Archives of General Psychiatry, which found that the rate of their use by people ages 6 and older nearly doubled from 1996 to 2005.While the authors say the increase is probably due to a cluster of factors—such as more antidepressant options on the market, their expanded use to treat conditions other than depression, and direct-to-consumer advertising—their changing reputation in the public eye has most likely also played a part, says psychiatrist Ramin Mojtabai, an associate professor in the department of mental health at the Johns Hopkins Bloomberg School of Public Health, who was not involved in the new study.

"While there's good news that people are more willing to take medications when they need [them], when there's an indication, they are also more willing to take them when there is no evidence-based reason to," says Mojtabai, whose study of Americans' opinions on psychiatric medications appears in the current issue of Psychiatric Services. Indeed, in comparing the opinions of 1,387 survey respondents in 1998 with those of 1,437 respondents in 2006, he found that people appear increasingly willing to takeantidepressants and other psychiatric medications for symptoms of depression and panic attacks but also for "very common distressing experiences" that "are not psychiatric disorders"—like everyday stress and interpersonal problems.

Although the survey only asked questions about hypothetical situations, not questions about actual behavior, Mojtabai says his findings raise questions about whether the public understands for whom antidepressants are truly effective. "Medications are not always safe," he says. "There are problems with taking [them] when there's no real indication." Antidepressants can indeed be lifesaving when clinically appropriate, he says, but his findings suggest that confusion may abound about what that means. Here are three not-so-great reasons to consider an antidepressant:

1. To improve relationships with family and friends. When asked about the benefits of psychiatric medications, more people surveyed in 2006 than in 1998 said they'd be willing to take them to ease trouble in their personal life, and more people thought the meds could "make things easier in relations with family and friends," Mojtabai found. But unless a psychiatric disorder is at the root of one's relationship woes, there's no reason to think that antidepressants would help, says Mojtabai—though people taking antidepressants for depression, which often leads to social withdrawal and isolation, may notice improvements in their interpersonal relationships as their underlying condition improves.

2. To raise self-esteem. More respondents in the later survey thought psychiatric medications would "help people feel better about themselves," Mojtabai found. Again, he says: "We know that if a person doesn't feel bad about themselves because of a psychiatric disorder, then there's really not much evidence that [antidepressants] are helpful."

3. To deal with day-to-day stress. By 2006, more people also believed that psychiatric medications "help people to deal with day-to-day stresses" and were willing to take them to cope with those, Mojtabai found. Yet, unless there's some underlying psychiatric illness, "there's not much evidence that these medications help people deal with day-to-day stresses" such as problems at the office, he says.

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